April 2, 2018
April 2, 2018 —
The vast majority of genetic mutations associated with cancer occur in non-coding regions of the genome, yet it’s unclear how they may influence tumor development or growth. Researchers at University of California San Diego School of Medicine and Moores Cancer Center identified nearly 200 mutations in non-coding DNA that play a role in cancer. Each mutation could represent a new cancer drug target. The study is published April 2 in Nature Genetics.
March 29, 2018
March 29, 2018 —
Rapid treatment is crucial when treating a stroke because, during an event, as many as 2 million neurons may die with each passing minute. Lifesaving interventions administered quickly and effectively not only save lives but also limit disabilities associated with the condition. A recent data analysis conducted by the American Heart Association (AHA) showed that the Comprehensive Stroke Centers at UC San Diego Health exceeded national average treatment times and, as a result, UC San Diego Health received Gold Plus Achievement status and the Honor Roll Elite Plus award for stroke care.
March 27, 2018
March 27, 2018 —
UC San Diego Health has been named a “Leader in LGBTQ Healthcare Equality” by the Human Rights Campaign (HRC) Foundation, the educational arm of the nation’s largest lesbian, gay, bisexual, transgender and queer civil rights organization.
March 26, 2018
March 26, 2018 —
Receptivity to advertising for e-cigarettes, cigarettes and cigars were confirmed to be associated with those who would try the respective tobacco product within one year. However, receptivity to e-cigarette advertising also independently increased the odds that 12- to 21-year-olds who have never smoked would try cigarette smoking within the next year by 60 percent. This finding, publishing in the March 26 issue of JAMA Pediatrics, was independent of receptivity to cigarette advertising.
March 13, 2018
March 13, 2018 —
Each year, at precisely the same moment — 12 p.m. on the East coast, 9 a.m. on the West — thousands of graduating medical school students across the country simultaneously tear open an envelope. The single sheet of paper inside informs each graduate where he or she will do their residencies. This rite of passage for medical students will mark a new chapter in their already remarkable stories. Here are three.
March 9, 2018
March 9, 2018 —
Fueled by a multimillion dollar grant from the state’s stem cell agency, researchers at University of California San Diego School of Medicine, in collaboration with local biotechnology company Oncternal Therapeutics, have launched a phase Ib/II clinical trial to evaluate the combined effectiveness of a standard of care drug with a novel monoclonal antibody that target B-cell malignancies, which include leukemias and lymphomas.
March 8, 2018
March 8, 2018 —
Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings, they say, represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH.
March 7, 2018
March 7, 2018 —
UC San Diego Health is the first hospital in California to use the fifth generation troponin test to diagnose heart attack. Approved in the United States in 2017, the more sensitive test can detect heart attack within an hour, as opposed to three to six hours.
March 6, 2018
March 6, 2018 —
The study, published in the March 5 online edition of the Proceedings of the National Academy of Sciences (PNAS), describes how the supercomputing power of Gordon, Comet, and GPU clusters, all based at the San Diego Supercomputer Center at UC San Diego, were used with improved accelerated molecular dynamics (aMD) or Gaussian aMD (GaMD) to simulate the merger of a G-protein “mimetic nanobody” to a G-protein-coupled receptor (GPCR), the largest and most diverse group of membrane receptors in animals, plants, fungi, and protozoa.
March 5, 2018
March 5, 2018 —
On March 12, 2018, UC San Diego Health will welcome its first patients to the Koman Family Outpatient Pavilion. Located on the La Jolla campus, the new 156,000-square-foot facility represents the most recent addition to the university’s world-class medical campus. In the past five years, UC San Diego Health has invested more than $1.3 billion dollars in patient care facilities for the community.
