February 27, 2018
February 27, 2018 —
Writing in the February 27 online issue of Science Signaling, researchers at University of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and metastasis.
February 27, 2018
February 27, 2018 —
A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing mutations and could enable researchers to discover new uses for existing drug treatments.
February 26, 2018
February 26, 2018 —
Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries. The grafts not only survived, but grew hundreds of thousands of human axons and synapses, resulting in improved forelimb function in the monkeys.
February 22, 2018
February 22, 2018 —
Using artificial intelligence and machine learning techniques, researchers at Shiley Eye Institute at UC San Diego Health and University of California San Diego School of Medicine, with colleagues in China, Germany and Texas, have developed a new computational tool to screen patients with common but blinding retinal diseases, potentially speeding diagnoses and treatment.
February 20, 2018
February 20, 2018 —
UC San Diego Health now offers patients with epilepsy another non-pharmacological way to treat seizures. For the more than one million individuals who live with uncontrolled seizures despite taking medications, UC San Diego Health recently began offering the first and only FDA-approved brain-responsive neurostimulation (RNS) system designed for the treatment of refractory epilepsy.
February 14, 2018
February 14, 2018 —
Researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health have discovered that a chemical compound that activates ATF6, a gene associated with an inherited vision impairment, also converts patient-derived stem cells into blood vessels.
February 13, 2018
February 13, 2018 —
The first datasets from the largest long-term study of brain development and child health in the United States—a project headed by a team of scientists at UC San Diego—were released to researchers around the world today by the National Institutes of Health.
February 13, 2018
February 13, 2018 —
Aswini Krishnan, a fourth-year bioengineering major at the University of California San Diego, has been awarded a Churchill Scholarship, one of the most prestigious and competitive awards available to American students pursuing science, mathematics and engineering fields. The award provides one year of funding to pursue a master’s degree at Winston Churchill College at the University of Cambridge. Krishnan is the fourth UC San Diego student to receive the award since the program’s inception in 1963.
February 8, 2018
February 8, 2018 —
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a paper publishing in Cell on February 8, University of California San Diego School of Medicine researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
February 7, 2018
February 7, 2018 —
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.
