News Archive - Mario Aguilera

New Technology Designed to Genetically Control Disease-spreading Mosquitoes

Scientists have created the precision-guided sterile insect technique, a new CRISPR-based technology to control Aedes aegypti, the mosquito species responsible for spreading wide-ranging diseases including dengue fever, chikungunya and Zika.

Growth-promoting, Anti-aging Retinal at the Root of Plant Growth Too

Publishing in the journal Science, a research team led by new UC San Diego biologist Alexandra Dickinson has identified a compound that plays a key role in triggering the development of plants’ lateral roots. Retinoids, known for medical uses, were found to be vital in plant growth.

UC San Diego Researchers Discover Key Mechanisms behind Synapse Degeneration in Alzheimer’s Brain

Neurobiologists have uncovered the mechanisms behind the maintenance and decline of key synapses implicated in Alzheimer’s disease. The findings suggest an alternative approach to addressing such brain disorders.

Diamonds Are a Physicist’s Best Friend

Physics condensed matter experimentalist Chunhui Rita Du leverages imperfections in diamonds to investigate materials needed for a new era of computing and storage. New quantum materials are exotic substances that are allowing scientists to create novel technologies at previously unseen scales.

Trained Viruses Prove More Effective at Fighting Antibiotic Resistance

Research reveals that phage viruses that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope for the antibiotic resistance crisis, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.

Synthetic SPECIES Developed for Use as a Confinable Gene Drive

Scientists have developed a gene drive with a built-in genetic barrier that is designed to keep the drive under control. The researchers engineered synthetic fly species that, upon release in sufficient numbers, act as gene drives that can spread locally and be reversed if desired.

Researchers Create New CRISPR Tools to Help Contain Mosquito Disease Transmission

Scientists have developed a toolkit that helps pave the way to a gene drive designed to stop Culex mosquitoes from spreading disease. Culex mosquitoes spread devastating afflictions stemming from West Nile virus, Japanese encephalitis virus and the pathogen causing avian malaria.

Research Uncovers How ‘Non-professional’ Cells Can Trigger Immune Response

Researchers are finding new details on the complex dynamics involved in how organisms sense an infection from pathogens. The researchers found that worms can sense changes in their metabolism in order to unleash protective defenses, even if they don’t directly sense an incursion from pathogens.

Plant Consumers Play Unexpectedly Large Role in the Evolution of Seedling Success

Scientists have found that herbivores have a lot to say about plant evolution and determining the success of seedlings. The influence of birds, rabbits, mice and other herbivores likely counteracts early plant emergence due to climate change, the researchers found.

New Genetic ‘CopyCatchers’ Detect Efficient and Precise CRISPR Editing in a Living Organism

Scientists have developed a novel CRISPR-based genetic sensor called a “CopyCatcher” to detect instances in which a genetic element is copied precisely from one chromosome to another in cells of a fruit fly.