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Laying the Groundwork for Potential Age-Related Macular Degeneration Therapies

The study published in Proceedings of the National Academy of Sciences (PNAS) suggests that heparan sulfate (HS) in Bruch’s membrane is a major player in early AMD by trapping lipoproteins and kickstarting drusen formation.

UC San Diego Researchers Find Evidence of Accelerated Aging in Children with Multiple Sclerosis

The study focused on children and teenagers not yet impacted by the processes of normal aging and age-related illnesses like hypertension and diabetes. Despite appearing outwardly healthy, children with MS showed DNA patterns indicating they were biologically older than their peers.

Understanding the Mechanisms of Embryonic Cell Behavior

During embryonic development, thousands of cells divide and move as one. Understanding the mechanisms that coordinate this collective behavior remains a significant challenge in biology and the physics of living systems. Researchers from UC San Diego have discovered that avian embryos control their

Recognizing Sex Differences in Disease Can Improve Treatments for All

A new study shows that drug treatment outcomes are significantly different for a type of heart valve disease based on how the disease progresses in males versus females. An AI-derived digital medicine platform can help optimize drug therapies based on cellular-scale sex differences.

Molecule Linked to Metabolism Found to Boost Plant Growth

Researchers have completed the first comprehensive exploration of itaconate, a natural compound involved in metabolism, in plants. The researchers found that itaconate helps plants grow, a finding that offers new possibilities for maximizing crop growth to support growing global populations.

Alzheimer’s Gene Therapy Shows Promise in Preserving Cognitive Function

By reprogramming brain cells, a new gene therapy approach for Alzheimer's developed by UC San Diego researchers could address the root cause of the disease to halt its progression.

Annual Carbon Dioxide Peak Passes Another Milestone

For the first time, the seasonal peak of carbon dioxide concentrations in the atmosphere exceeded 430 parts per million (ppm) at NOAA’s Mauna Loa Observatory on Hawaii, scientists from NOAA and Scripps Institution of Oceanography at the University of California San Diego reported today.

Celebrating 50 Years of Training Physician-Scientists

The Medical Scientist (M.D./Ph.D.) Training Program (MSTP) at the University of California San Diego School of Medicine is celebrating 50 years of training physician-scientists who strive to bridge two worlds, the clinic and the lab.

A Better Understanding of How Gene Editing Tools Work

Patients are being healed with a personalized treatment that repairs the patient’s specific genetic mutation. The treatment was created using a form of gene editing called base editing —a method created by UC San Diego’s Alexis Komor. Her latest research outlines the way certain DNA repair proteins

Producer, Photographer, Statistician: These Tritons Do it All

UC San Diego's scholar-athletes may be making the headlines, but behind every game a group of student employees ensures it all runs smoothly. From live production and photography to statistical analysis, these dedicated students bring their Triton pride and enthusiasm to each game.

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