September 20, 2019
Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.
March 27, 2017
Researchers led by Karen Christman, a bioengineering professor at the University of California San Diego, were awarded nearly $3.1 million by the governing Board of the California Institute for Regenerative Medicine March 23. Their work aims to help people with peripheral arterial disease. The condition narrows and blocks arteries providing…
August 10, 2017
…Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic mechanisms that drive AGS and test strategies to inhibit the condition…
August 4, 2016
…receive a new type of immunotherapy, known as CAR T-cell therapy, as part of a Phase I/II clinical trial at Moores Cancer Center at UC San Diego Health.
December 3, 2018
Following the FDA’s approval of chimeric antigen receptor (CAR) T-cell therapies for the treatment of certain types of non-Hodgkin lymphomas, UC San Diego Health was the first medical center in San Diego to be certified to offer this type of immunotherapy outside of a clinical trial.
July 8, 2019
UC San Diego will launch a payload of stem cell-derived human brain organoids to the International Space Station. Researchers will document how these “mini brains” organize into the beginnings of a functional brain with implications for the future of human life in space.
April 4, 2019
An international team of scientists led by researchers at University of California San Diego School of Medicine employed an array of next-generation sequencing and gene-editing tools, such as CRISPR, to map the molecular dependencies – and thus vulnerabilities – of pancreatic cancer stem cells.
October 10, 2011
…genes and molecules to cells and tissues to organs and systems. Some of his more recent research has focused on the effects of mechanical forces – pressure and flow – on cellular functions such as gene expression. When genes change their expression, the proteins will change, and proteins are the…
February 11, 2021
UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.
October 27, 2017
Researchers at the University of California San Diego School of Medicine, with colleagues in Brazil, report that the Zika virus is transmitted from mother to fetus by infected cells that, ironically, will later develop into the brain’s first and primary form of defense against invasive pathogens.
