November 12, 2020
…and application of green fluorescent protein (GFP), which allows some jellyfish to glow. While colleagues discovered and isolated the GFP gene, Tsien found ways to tweak its makeup, making it glow more brightly and consistently. Then, he created a full color palette of fluorescent proteins that scientists could use to…
May 5, 2022
…activity, and release a fluorescent signal in the exact location where activity is increased. Their studies, published in February 2020 and December 2021, were the first demonstration of a sensor that could detect protease activity to identify and locate TBI in mice. Researchers in Kwon’s lab were the first to…
August 25, 2022
…isolate and verify two fluorescent cells. The duo learned how to prepare cells for expression and purification, and how to perform transfections. José Eduardo Martín Llamas and Nicolas Mosqueda spent the summer in mechanical engineering Professor James Friend’s lab. “I thought it wasn’t going to be so professional,” Garcia Martinez…
July 26, 2011
UC San Diego recently completed a $1.5 million lighting-retrofit project that has reduced electricity costs by $210,000 per year in campus offices, classrooms and meeting rooms, warehouses and other areas.
September 21, 2011
Biologists at the University of California, San Diego have identified more than 70 genes that play a role in regenerating nerves after injury, providing biomedical researchers with a valuable set of genetic leads for use in developing therapies to repair spinal cord injuries and other common kinds of nerve damage…
November 17, 2011
The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body’s response to healing skin wounds, a serious problem in diabetics and the elderly.
November 21, 2011
A study using genetically modified zebrafish to visualize early events involved in development of human atherosclerosis describes an efficient model – one that the researchers say offers many applications for testing the potential effectiveness of new antioxidant and dietary therapies.
January 25, 2012
Researchers at the University of California, San Diego School of Medicine have created a new generation of fast-acting fluorescent dyes that optically highlight electrical activity in neuronal membranes. The work is published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences.
April 12, 2012
A study conducted on roundworms by biologists at UC San Diego has uncovered some important clues to answering the question of how humans and other animals are able to discriminate between disease-causing microbes and innocuous ones to rapidly respond to infections.
July 26, 2012
For Nobel laureate Roger Tsien, the drive to help find a cure for cancer stems from personal experience. His father battled prostate cancer and ultimately lost his life to pancreatic cancer. As a professor of pharmacology, chemistry and biochemistry at UC San Diego and a Howard Hughes Medical Institute investigator,…
