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Your search for “fluorescence” returned 168 results

Nanosponge Vaccine Fights MRSA Toxins

December 2, 2013

Nanosponges that soak up a dangerous pore-forming toxin produced by MRSA (methicillin-resistant Staphylococcus aureus) could serve as a safe and effective vaccine against this toxin. This “nanosponge vaccine” enabled the immune systems of mice to block the adverse effects of the alpha-haemolysin toxin from MRSA—both within the bloodstream and on…

The Brain’s Balancing Act

June 22, 2014

Researchers at the University of California, San Diego School of Medicine have discovered a fundamental mechanism by which the brain maintains its internal balance. The mechanism, described in the June 22 advanced online publication of the journal Nature, involves the brain’s most basic inner wiring and the processes that control…

Dramatic Growth of Grafted Stem Cells in Rat Spinal Cord Injuries

August 7, 2014

Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran’s Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons…

New Nano3 Microscope Will Allow High-Resolution Look Inside Cells

August 8, 2014

The University of California, San Diego’s Nanofabrication Cleanroom Facility (Nano3) is the first institution to obtain a novel FEI Scios dual-beam microscope, with an adaptation for use at cryogenic temperatures. The new microscope will enable research among a highly diverse user base, ranging from materials science to structural and molecular…

Quantitative Biology Approach Reveals Importance of Physical Constraints on Critical DNA Interaction

August 13, 2014

Our immune system copes with a multitude of threats using a mix-and-match system to create millions of different antibodies.

Four UC San Diego Faculty Win ‘Early Concept’ Grants from Obama’s BRAIN Initiative

August 18, 2014

Four scientists at UC San Diego are among 36 recipients nationwide who have been awarded early concept grants for brain research from the National Science Foundation, the agency announced today.

Real-time Readout of Neurochemical Activity

October 27, 2014

Scientists have created cells with fluorescent dyes that change color in response to specific neurochemicals. By implanting these cells into living mammalian brains, they have shown how neurochemical signaling changes as a food reward drives learning, they report in Nature Methods online October 26.

Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria

November 25, 2014

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.

Early Retina Cell Changes in Glaucoma Identified

February 11, 2015

To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease. Their study, published Feb. 10 in The Journal of Neuroscience, reveals how…

New Insights into 3D Genome Organization and Genetic Variability

February 18, 2015

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren’t encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of…

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