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Your search for “Therapy Target” returned 457 results

Early Biomarker for Pancreatic Cancer Identified

May 15, 2012

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention.

NIH Awards $6.9 Million to Advance Potential Alzheimer’s Disease Treatment

August 20, 2024

Researchers from UC San Diego are working on a new treatment for Alzheimer’s that targets tau - a type of protein in the brain that helps cells retain their stability and structure.

“Soft” CRISPR May Offer a New Fix for Genetic Defects

July 1, 2022

Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.

SDSC/UCSD Study Uncovers Mechanisms of Cancer-Causing Mutations

March 18, 2015

Researchers at the San Diego Supercomputer Center (SDSC) and the Moores Cancer Center at the University of California, San Diego, have described for the first time the molecular mechanism of cancer development caused by well-known “resistance” mutations in the gene called epidermal growth factor receptor (EGFR).

UC San Diego Launches Gene Therapy Initiative, Targeting Treatments for Rare Diseases

August 29, 2023

A $5 million gift from the Nancy and Geoffrey Stack Foundation has established the UC San Diego Gene Therapy Initiative to find novel therapies for children and adults with genetic diseases.

Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery

July 12, 2021

Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

Medical Innovator: Farah Sheikh

April 1, 2024

UC San Diego researcher, Farah Sheikh, studies a genetic heart arrhythmia condition that usually strikes people under 40. Her research will be used in clinical trials of a treatment for ARV.

With OK From FDA, UC San Diego Researchers Prepare to Launch Novel Phage Study

January 8, 2019

FDA approves first U.S. clinical trial of an intravenously administered bacteriophage-based therapy to treat resistant bacterial infections.

Opioid Dependence Found to Permanently Change Brains of Rats

January 24, 2020

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.

Stem Cell-Derived Therapy Shows Promise Against Treatment-Resistant Liver Cancer

July 9, 2024

Discover research from UC San Diego showing how stem cell-derived therapy, targeting treatment-resistant liver cancer through genetically modified NK cells, offers promising new avenues for immunotherapy.

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