October 3, 2019
UC San Diego researchers investigated how a type of immune cell called a macrophage becomes specialized to the liver. Their study, published October 3, 2019 in Immunity, sets the stage for understanding how macrophage specialization gets disrupted by — or contributes to — liver disease.
August 22, 2016
…widespread medical problems, scientists were uncertain about how these single-celled fungi reproduced in human or animal cells. But in a study that employed transparent roundworms, biologists at the University of California San Diego succeeded in directly observing how these microorganisms replicate and spread. And what they saw surprised them.
July 9, 2024
Discover research from UC San Diego showing how stem cell-derived therapy, targeting treatment-resistant liver cancer through genetically modified NK cells, offers promising new avenues for immunotherapy.
September 20, 2018
…researchers found that CD4+ T cell’s binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.
October 7, 2021
UC San Diego study suggests multisystem inflammatory syndrome in children (MIS-C), a rare condition associated with COVID-19, is not caused by abnormal T cell response to COVID-19 virus as previously hypothesized.
October 30, 2015
The brain cells of patients with bipolar disorder, a manic-depressive illness characterized by severe swings in mood, energy and ability to carry out daily tasks, are more sensitive to stimuli than other people’s brain cells, reports an international team of scientists headed by researchers at Salk Institute for Biological Studies…
November 8, 2017
…inflammation directly affects cancer cells, stimulating their division and protecting them from cell death. But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes cancer by suppressing immunosurveillance — a natural defense mechanism in which it’s thought the immune system suppresses…
July 20, 2017
…researchers to develop a new immunotherapy in which patients’ cells would be equipped with a special receptor that recognizes and targets cancer stem cells, whose survival abilities often render standard therapies ineffective or short-term.
September 17, 2015
Visible Molecular Cell Consortium will build bridges between disciplines and institutions to assemble and simulate a virtual model of a cell, down to an atomic level of detail.
October 1, 2014
…advance treatments for type 1 diabetes. Using human stem cells, the team plans to culture bits of human pancreas in a dish and, using microfluidics, mimic blood flow through the islet.
