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Your search for “DNA Mutations” returned 153 results

Blood Biopsy Reveals Unique, Targetable Genetic Alterations in Patients with Rare Cancer

August 15, 2017

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

Microbial DNA in Patient Blood May be Tell-Tale Sign of Cancer

March 11, 2020

From a simple blood draw, microbial DNA may reveal who has cancer and which type, even at early stages.

Rare Genetic Mutations Linked To Bipolar Disorder

December 21, 2011

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder.

Oncogene Mutation Hijacks Splicing Process to Promote Growth and Survival

May 31, 2013

…of Medicine – has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

Looking Beyond DNA to See Cancer with New Clarity

September 30, 2021

In three Science papers, UC San Diego and UC San Francisco researchers mapped out how hundreds of gene mutations involved in cancer affect the discrete groups of proteins that are the ultimate actors behind the disease. The work points the way to identifying new precision treatments.

AI Harnesses Tumor Genetics to Predict Treatment Response

January 18, 2024

Cancer resists treatment in a multitude of ways, but a new algorithm developed by scientists at UC San Diego can decode them all simultaneously.

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

October 1, 2017

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.

In Cells, UV-Emitting Nail Polish Dryers Damage DNA and Cause Mutations

January 17, 2023

The ultraviolet nail polish drying devices used to cure gel manicures may pose more of a public health concern than previously thought. Researchers at UC San Diego studied these UV light-emitting devices, and found that their use leads to cell death and cancer-causing mutations in human cells.

Enzymes Can’t Tell Artificial DNA From the Real Thing

December 13, 2023

Researchers from UC San Diego have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.

UC San Diego, UC San Francisco Launch New Cancer Cell Mapping Initiative

January 29, 2015

Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project – dubbed the Cancer Cell Map Initiative or CCMI – to determine how all of the components of a…

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