February 6, 2024
UC San Diego scientists have shown that they can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts.
October 1, 2012
Two proteins previously found to contribute to ALS, also known as Lou Gehrig’s disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine, shows that a common pathway links them.
December 5, 2017
Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.
February 16, 2023
UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.
January 23, 2020
…the Cystinosis Research Foundation, California Institute for Regenerative Medicine (CIRM), and National Institutes of Health. She receives additional support from the Sanford Stem Cell Clinical Center and CIRM-funded Alpha Stem Cell Clinic at UC San Diego Health, and AVROBIO.
December 8, 2020
UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.
July 2, 2020
…Institute for Regenerative Medicine (CIRM), and Maxine Adler Endowed Chair Funds. An earlier version of this paper was shared as a preprint on BioRxiv on November 19, 2019, prior to peer-review and publication in Cell Systems. Disclosure: Trey Ideker is co-founder of Data4Cure, Inc., is on the Scientific Advisory Board,…
September 19, 2012
Five University of California, San Diego graduate students pursuing research at the intersection of bioengineering, medicine and biology are among the 85 recipients of 2013 Siebel Scholars awards, announced by the Siebel Scholars Foundation on September 10, 2012.
August 29, 2019
Nine-month-old brains-in-a-dish and the brains of premature newborn babies generate similar electrical patterns, as captured by electroencephalogram (EEG) — the first time such brain activity has been achieved in a cell-based laboratory model.
January 16, 2020
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink…
