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Your search for “CIRM” returned 69 results

Computational Modeling Results in New Findings for Preeclampsia Patients

July 12, 2021

According to the Centers for Disease Control and Prevention, preeclampsia, or pregnancy-related hypertension, occurs in roughly one in 25 pregnancies in the United States. The causes are unknown and childbirth is the only remedy, which can sometimes lead to adverse perinatal outcomes

Two Anti-viral Enzymes Transform Pre-Leukemia Stem Cells into Leukemia

January 26, 2021

Viral infections and space travel similarly trigger inflammation and the enzymes APOBEC3C and ADAR1; UC San Diego researchers are developing ways to inhibit them as a means to potentially lower cancer risk for both astronauts and people on Earth.

$150 Million Gift Takes Stem Cell Research to New Heights

September 6, 2022

Noted businessman and philanthropist T. Denny Sanford has committed $150 million in new funding to expand and, in some ways, quite literally launch stem cell research and regenerative medicine at University of California San Diego into new spaces and endeavors.

Stem Cell ‘Collaboratory’ Opens on UC San Diego Campus

December 6, 2011

…Institute for Regenerative Medicine (CIRM), a state agency established in 2004 with the passage of Proposition 71 and charged with overseeing $3 billion in tax-supported funding for stem cell research at California universities and research institutions. UC San Diego research alone has received more than $100 million in CIRM funding…

Spotlight on Faculty Research: Stem Cell

November 14, 2011

…stem cells. As a CIRM New Faculty Award winner, Dr. Traver will determine the genetic factors necessary to create HSCs from mesoderm by applying the unique advantages of the zebrafish system. Zebrafish embryos are transparent, and he has recently created transgenic animals that possess fluorescent HSCs. His group can therefore…

Designer DNA Therapeutic Wipes Out Cancer Stem Cells, Treats Multiple Myeloma in Mice

January 20, 2021

UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent — an antisense oligonucleotide that targets a gene called IRF4 — in patients with multiple myeloma.

Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

December 10, 2019

People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.

Researchers Block Pathway to Cancer Cell Replication

July 3, 2012

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…

UC San Diego to Advance Stem Cell Therapies in New Space Station Lab

April 8, 2020

UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.

Promise Put to the Test

October 20, 2014

UC San Diego Sanford Stem Cell Clinical Center is pushing therapeutic stem cell-based science out of the laboratory and closer to real-world medical applications. The unprecedented trials involve potential therapies for spinal cord injuries, Type 1 diabetes and chronic lymphocytic leukemia.

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