September 6, 2022
Noted businessman and philanthropist T. Denny Sanford has committed $150 million in new funding to expand and, in some ways, quite literally launch stem cell research and regenerative medicine at University of California San Diego into new spaces and endeavors.
December 6, 2011
…Institute for Regenerative Medicine (CIRM), a state agency established in 2004 with the passage of Proposition 71 and charged with overseeing $3 billion in tax-supported funding for stem cell research at California universities and research institutions. UC San Diego research alone has received more than $100 million in CIRM funding…
November 14, 2011
…stem cells. As a CIRM New Faculty Award winner, Dr. Traver will determine the genetic factors necessary to create HSCs from mesoderm by applying the unique advantages of the zebrafish system. Zebrafish embryos are transparent, and he has recently created transgenic animals that possess fluorescent HSCs. His group can therefore…
January 20, 2021
UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent — an antisense oligonucleotide that targets a gene called IRF4 — in patients with multiple myeloma.
December 10, 2019
People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.
July 3, 2012
Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…
April 8, 2020
UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.
October 20, 2014
UC San Diego Sanford Stem Cell Clinical Center is pushing therapeutic stem cell-based science out of the laboratory and closer to real-world medical applications. The unprecedented trials involve potential therapies for spinal cord injuries, Type 1 diabetes and chronic lymphocytic leukemia.
September 27, 2016
The underlying cause of male infertility is unknown for 30 percent of cases. In a pair of new studies, researchers at University of California San Diego School of Medicine determined that the reproductive homeobox (RHOX) family of transcription factors — regulatory proteins that activate some genes and inactivate others —…
October 20, 2016
Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic material. University of California San Diego School of Medicine researchers studied several ALS cases with a mutation in a…
