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Your search for “CIRM” returned 68 results

Machine Learning Algorithm Can’t Distinguish These Lab Mini-Brains from Preemie Babies

August 29, 2019

Nine-month-old brains-in-a-dish and the brains of premature newborn babies generate similar electrical patterns, as captured by electroencephalogram (EEG) — the first time such brain activity has been achieved in a cell-based laboratory model.

Cancer Drug Could Ease Cognitive Function for Some With Autism

July 25, 2024

An experimental cancer drug could ease cognition for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the Muotri Lab at the University of California San Diego — a discovery that could lead to therapies for patients with other neurologic conditions.

Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer Cells

January 16, 2020

Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink…

The Explorers: A Passion for Science Leads to New Territory

April 6, 2023

After decades of working in industry and academia, biophysicists Alex Savtchenko and Elena Molokanova still have big dreams.

Novel Drug Targeting Leukemia Cells Enters Clinical Trial

September 16, 2014

Researchers at the University of California, San Diego School of Medicine have launched a phase 1 human clinical trial to assess the safety and efficacy of a new monoclonal antibody for patients with chronic lymphocytic leukemia (CLL), the most common form of blood cancer in adults.

Anti-Leukemia Drug May Also Work Against Ovarian Cancer

November 17, 2014

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine.

Protein-Protein Interaction Activates and Fuels Leukemia Cell Growth

December 21, 2015

Building upon previous research, scientists at University of California, San Diego School of Medicine and UC San Diego Moores Cancer report that a protein called Wnt5a acts on a pair of tumor-surface proteins, called ROR1 and ROR2, to accelerate the proliferation and spread of chronic lymphocytic leukemia (CLL) cells, the…

UC San Diego Sparks New Cancer-Focused Startup, Oncternal, with Exclusive Antibody License

May 2, 2016

Oncternal Therapeutics, a new cancer-focused biotechnology startup, has signed a wide-ranging licensing agreement with UC San Diego to develop and commercialize antibodies and antibody-related binding agents.

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