January 27, 2022
A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer’s disease.
May 3, 2022
…older adults could be an early warning sign of Alzheimer’s disease. Research led by UC San Diego has consistently found high levels of PHGDH expression in brain tissue and blood samples of older adults with different stages of the disease.
April 6, 2012
Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer’s disease (AD).
August 9, 2023
Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.
December 16, 2013
Down syndrome (DS) is a childhood condition but improved health care means that individuals with DS now routinely reach age 50 or 60 years of age, sometimes beyond. However, if they live long enough, people with Down syndrome are almost certain to develop Alzheimer’s disease.
March 7, 2012
…for improving memory deficits and reducing the pathology of Alzheimer’s disease (AD) in an animal model representative of most AD patients.
November 21, 2023
UC San Diego’s Center for Scientific Computation in Imaging has received a $7.5 million grant from the National Institutes of Health to continue its interdisciplinary exploration of diffusion magnetic resonance imaging (dMRI) work related to Alzheimer’s disease.
May 14, 2024
…and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex.
April 11, 2016
…fragment that accumulates in the brains of people with Alzheimer’s disease.
August 15, 2012
Sticky plaques of proteins called amyloids mark several different, though related degenerative brain diseases including Alzheimer’s, Parkinson’s and Creutzfeld-Jacobs. The symptoms of these disorders overlap and methods to diagnose and monitor them are not very advanced.
