A team of doctors and scientists, led by researchers at the University of California, San Diego School of Medicine and the Howard Hughes Medical Institute, say de novo somatic mutations in a trio of genes that help regulate cell size and proliferation are likely culprits for causing hemimegalencephaly, though perhaps not the only ones.
Psoriasis is an autoimmune disorder in which skin cells proliferate out of control. For some hard-to-heal wounds, the problem is just the opposite: Restorative skin cells don’t grow well or fast enough. In a paper published in the June 21, 2012 issue of Immunity, researchers at the University of California, San Diego School of Medicine describe a molecule that may lead to new treatments for both problems.
Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single gene to produce or code multiple types of protein variants. The discovery, published in the June 27, 2012 issue of Molecular Cell, suggests the new pathway might be a fruitful target for new cancer drugs.
With a single drug treatment, researchers at the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine can silence the mutated gene responsible for Huntington’s disease, slowing and partially reversing progression of the fatal neurodegenerative disorder in animal models.
UC San Diego Health System has been recognized as a “Leader in LGBT Healthcare Equality” in the Healthcare Equality Index 2012 report, an annual survey conducted by the Human Rights Campaign (HRC) Foundation.
Anyone who has seen a newborn in a hospital NICU knows the image is shocking. Wires and electrodes designed to monitor vital signals such as heart rate, brain signals and blood oxygen levels are taped over the frail newborn’s head, face and body. Skin-to-skin contact between mom and baby that doctors say all newborns need to develop a sense of security and bonding becomes challenging, if not impossible. Parents seeing their precious baby this way may also feel terrified and helpless.
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