Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now. In a paper, University of California San Diego School of Medicine researchers identified exosomes — extremely small vesicles or sacs secreted from most cell types — as the missing link.
Scientists have found that ignored pieces of DNA play a critical role in the development of immune cells called T cells. These areas activate a change in the 3D structure of DNA that brings together crucial elements necessary for T cell formation. This “big bang” discovery may be unfolding throughout the animal and plant kingdoms as well as aid in combating diseases such as lymphoma and leukemia.
Checkpoint inhibitor-based immunotherapy has been shown to be very effective in recurrent and metastatic head and neck cancer but only in a minority of patients. University of California San Diego School of Medicine researchers may have found a way to double down on immunotherapy’s effectiveness.
Researchers have demonstrated a new mode of electromagnetic wave, called a "line wave," which has potential applications in areas ranging from integrated photonics, sensing and quantum processes to future vacuum electronics.
Researchers at University of San Diego School of Medicine have developed a new tool called the San Diego Wisdom Scale (SD-WISE) to assess an individual’s level of wisdom, based upon a conceptualization of wisdom as a trait with a neurobiological as well as psychosocial basis.
Just ahead of Hurricanes Irma and Maria, a UC San Diego research team was able to map and document various underwater and coastal features along Puerto Rico’s coast last month, providing baseline measurements of a number of important archaeological sites that are vulnerable to coastal erosion, particularly due to climate change.
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