Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.
Researchers at University of California San Diego School of Medicine report that autopsies of patients diagnosed with Alzheimer’s disease when they were alive — and confirmed by autopsy — indicate many cognitive issues symptomatic of the condition are less noticeable in living Hispanic patients.
A saucer-shaped arena set in the heart of Poland’s coal country seems like an unlikely place to host a global climate change conference. And yet, for two weeks in December, more than 20,000 delegates from nearly 200 nations converged to attend the 24th Conference of the Parties (COP24).
As a freshman at Lincoln High School, Lizbeth Roman knew that she wanted to achieve more than a high school diploma. She participated in a college readiness program and worked hard to maintain top grades with the goal of becoming the first in her family to attend a university.
A flurry of egg parachutes made with orange-tinted bubble wrap, duct tape, cardboard and trash bags rained down on the grounds outside UC San Diego’s Mayer Hall recently. A group of Generation Z aspiring physicists quickly checked the eggs to see if they have survived the long drop from one of the building’s balconies.
Using active genetics technology, biologists have developed the world’s first CRISPR/Cas9-based approach to control genetic inheritance in a mammal. The achievement in mice lays the groundwork for further advances based on this technology, including biomedical research on human disease.
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