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News Archive - Scott LaFee

Keeping Stem Cells Pluripotent

January 13, 2014

In a paper published in this week’s Online Early Edition of PNAS, researchers from the University of California, San Diego School of Medicine identify a key gene receptor and signaling pathway essential to maintaining hESCs in an undifferentiated state.

Treating the Inner Animal in All of Us

January 8, 2014

University of California, School of Medicine establishes a Center for Veterinary Sciences and Comparative Medicine - a highly integrated and innovative consortium of universities, institutions, scientists, physicians and veterinarians seeking to improve the condition of all animals.

The Mouse That ROR’ed

January 2, 2014

Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.

How Cells Remodel After UV Radiation

December 19, 2013

Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.

Total Smoking Bans Work Best

December 18, 2013

Completely banning tobacco use inside the home – or more broadly in the whole city – measurably boosts the odds of smokers either cutting back or quitting entirely.

UC San Diego Cancer Researchers Receive $4 Million CIRM Disease-Team Grant

December 13, 2013

Researcher Thomas J. Kipps, MD, PhD, professor of medicine and deputy director of research operations at UC San Diego Moores Cancer Center, is principal investigator for one of six “Disease Team” awards approved December 12 by the governing board of the California Institute for Regenerative Medicine (CIRM).

Brain Trauma Raises Risk of Later PTSD in Active-Duty Marines

December 11, 2013

In a novel study of U.S. Marines investigating the association between traumatic brain injury and the risk of post-traumatic stress disorder over time, a team of scientists led by researchers from the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine report that TBIs suffered during active-duty deployment to Iraq and Afghanistan were the greatest predictor for subsequent PTSD, but found pre-deployment PTSD symptoms and high combat intensity were also significant factors.

Brain Cancer Cells Hide While Drugs Seek

December 5, 2013

A team of scientists, led by Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.

Parasite Lost

November 27, 2013

Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria.

Using microRNA Fit to a T (cell)

November 25, 2013

Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes – which play a central role in the body’s immune response – with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA (miRNA).
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