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News Archive - Scott LaFee

Stuck on Flu

November 22, 2013

Researchers at the University of California, San Diego School of Medicine have shown for the first time how influenza A viruses snip through a protective mucus net to both infect respiratory cells and later cut their way out to infect other cells.

Understanding a Protein’s Role in Familial Alzheimer’s Disease

November 14, 2013

Researchers at the University of California, San Diego School of Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer’s disease (AD), discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.

$100 Million Gift Launches Sanford Stem Cell Clinical Center

November 4, 2013

In a bold and singular step toward delivering the therapeutic promise of human stem cells, businessman and philanthropist T. Denny Sanford has committed $100 million to the creation of the Sanford Stem Cell Clinical Center at the University of California, San Diego.

Child Brides at Funerals

October 28, 2013

Having children early and in rapid succession are major factors fueling high infant mortality rates in the South Asian countries of Bangladesh, India, Nepal and Pakistan where one in 14 births to young mothers ends with the death of the child within the first year, say researchers at the University of California, San Diego School of Medicine

Enzyme Restores Function with Diabetic Kidney Disease

October 25, 2013

Researchers at the University of California, San Diego School of Medicine say that, while a prevailing theory suggests elevated cellular levels of glucose ultimately result in diabetic kidney disease, the truth may, in fact, be quite the opposite. The findings could fundamentally change understanding of how diabetes-related diseases develop – and how they might be better treated.

Two UC San Diego Researchers Elected to Institute of Medicine

October 21, 2013

University of California, San Diego School of Medicine researchers Joseph G. Gleeson, MD, Howard Hughes Medical Institute investigator and professor of neurosciences and pediatrics, and Richard D. Kolodner, PhD, professor of medicine and Ludwig Cancer Research scientist, have been named new members of the Institute of Medicine, considered among the highest honors in the fields of health and medicine.

Costly Cigarettes and Smoke-Free Homes

October 17, 2013

Researchers at the University of California, San Diego School of Medicine say high-priced cigarettes and smoke-free homes effectively reduce smoking behaviors among low-income individuals – a demographic in which tobacco use has remained comparatively high.

The Role of “Master Regulators” in Gene Mutations and Disease

October 14, 2013

Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called “master regulators” read the genome, and consequently turn genes on and off.

Urine Biomarkers Reveal Mitochondrial Dysfunction in Diabetic Kidney Disease

October 10, 2013

Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites – small molecules produced by cellular metabolism – that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.

Researchers Identify Liver Cancer Progenitor Cells Before Tumors Become Visible

October 10, 2013

Researchers at the University of California, San Diego School of Medicine have isolated and characterized the progenitor cells that eventually give rise to malignant hepatocellular carcinoma tumors – the most common form of liver cancer. The researchers found ways to identify and isolate the HCC progenitor cells long before actual tumors were apparent.
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