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Your search for “stem cells” returned 506 results

CIRM Grants May Fund the Next Great Stem Cell Achievement

…ideas that might eventually impact the field of human stem cell research.

Dramatic Growth of Grafted Stem Cells in Rat Spinal Cord Injuries

…System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals’ central nervous system.

First Human In Vitro Model of Rare Neurodegenerative Condition Created

Researchers at University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego have created the first stem cell-derived in vitro cellular model of a rare, but devastating, neurodegenerative condition called Cockayne syndrome (CS).

Understanding a Protein’s Role in Familial Alzheimer’s Disease

…Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer’s disease (AD), discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.

Scientists Discover Neurochemical Imbalance in Schizophrenia

Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

…Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting.

Bipolar Patients’ Brain Cells Predict Response to Lithium

The brain cells of patients with bipolar disorder, a manic-depressive illness characterized by severe swings in mood, energy and ability to carry out daily tasks, are more sensitive to stimuli than other people’s brain cells, reports an international team of scientists headed by researchers at Salk Institute for Biological Studies…

Personalized “Eye-in-a-Dish” Models Reveal Genetic Underpinnings of Macular Degeneration

Using stem cells derived from six people, UC San Diego School of Medicine researchers recapitulated retinal cells in the lab. This “eye-in-a-dish” model allowed them to identify genetic variants that cause age-related macular degeneration, a common cause of vision loss.

Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity

UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.

UC San Diego Health Researchers Join Pancreatic Cancer “Dream Team”

…for their expertise in preclinical modeling, clinical trials and stem cell biology to join a “dream team” of international pancreatic cancer researchers.