October 11, 2023
Researchers at UC San Diego and the Icahn School of Medicine at Mount Sinai have been awarded an $8.5 million grant to create a data integration hub aimed at accelerating novel therapeutics and cures for diseases within initiatives supported by the NIH Common Fund.
February 1, 2024
UC San Diego scientists are working to flip the script on drug addiction with a $1.3 million grant from the W.M. Keck Foundation. Their new approach, called negative feedback chemogenetics, works by leveraging the body’s biochemical feedback processes to disrupt pathways associated with addiction.
February 22, 2016
Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016 in Nature Microbiology, identifies a…
August 15, 2017
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego and the University of Colorado Anschutz Medical Campus have found that compounds produced by the creosote bush, a desert plant common to the Southwestern United States, exhibit potent anti-parasitic activity against the protozoa responsible for…
August 12, 2020
The enzyme serine palmitoyl-transferase can be used as a metabolically responsive “switch” that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.
March 2, 2021
Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.
August 19, 2021
New visualizations of SARS-CoV-2 have allowed researchers to discover how the virus enters and infects healthy human cells. They found that glycan sugar molecules act as infection “gates” to our cell’s receptors.
November 12, 2021
…epidemics, while the Greek pharmacologist Pedanius Dioscorides prescribed agarikon to treat pulmonary infections 2,300 years ago. Though Western medicine still regards much of integrative medicine as lacking empirical, evidence-based proof, some of its ideas are gaining wider acceptance, such as acupuncture to treat pain and the herbal extract artemisinin to…
February 24, 2022
…of these studies. Communication across disciplines with chemists, biologist, pharmacologist, clinicians, and many more was essential to discovering the molecule, profiling it, and clinically testing it so that we could help people fighting this devastating disease today. I am incredibly grateful to each and every one of them.
April 22, 2019
University of California San Diego School of Medicine researchers found that treating patients with personalized precision medicine that combined therapies to target multiple alterations improved outcomes in patients with therapy resistant cancers.
