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Your search for “gene therapy” returned 764 results

Potential New Drug Class Hits Multiple Cancer Cell Targets, Boosting Efficacy and Safety

February 1, 2017

In a new paper published this week in PNAS, researchers at the University of California San Diego School of Medicine and Moores Cancer Center, in collaboration with colleagues at Rady Children’s Hospital-San Diego, the University of Colorado School of Medicine and SignalRx, a San Diego-based biopharmaceutical company, describe a potential…

UC San Diego Bioengineers Inducted Into Prestigious Biomedical Institution

March 17, 2022

Two bioengineers at the University of California San Diego will be inducted into the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). Professors Stephanie Fraley and Prashant Mali are among the 153 new AIMBE Fellows of 2022.

UC San Diego Among First in Nation to Treat Brain Cancer with Novel Viral Vector

March 1, 2012

UC San Diego Moores Cancer Center researchers and surgeons are among the first in the nation to treat patients with recurrent brain cancer by directly injecting an investigational viral vector into their tumor. The treatment is being developed by a local San Diego Company, Tocagen Inc.

Altered Cell Cycle Gene Activity Underlies Brain Overgrowth in Autistic Toddlers

December 14, 2015

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

ALS Study Reveals Role of RNA-Binding Proteins

October 20, 2016

…RNA, a type of genetic material. University of California San Diego School of Medicine researchers studied several ALS cases with a mutation in a RNA-binding protein known as hnRNP A2/B1. In the study, they describe how damage to this protein contributes to ALS by scrambling crucial cellular messaging systems.

Single Gene Mutation Linked to Diverse Neurological Disorders

October 9, 2013

…of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer’s, Parkinson’s and Huntington’s diseases.

Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

February 18, 2021

Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

October 1, 2017

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.

Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease

August 9, 2023

Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.

Extrachromosomal DNA is common in human cancer and drives poor patient outcomes

August 17, 2020

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including the University of California San Diego.

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