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Your search for “gene therapy” returned 772 results

Spotlight on Faculty Research: Autism

April 17, 2012

…the structural, functional, and genetic bases of this disorder. More… Lisa T. Eyler Lisa Eyler is an associate adjunct professor in the Department of Psychiatry. The focus of her research is exploring the structure and function of the brain in individuals across the lifespan. She is particularly interested in the…

Genetic Tweak Optimizes Drug-making Cells by Blocking Buildup of Toxic Byproduct

January 14, 2025

…autoimmune diseases and much more. By knocking out a gene circuit responsible for producing lactic acid—a metabolite that makes the cells’ environment toxic—researchers eliminate a primary hurdle in developing cells that can produce higher amounts of pharmaceuticals like Herceptin and Rituximab, without compromising their growth or energy production.

Enzyme Accelerates Malignant Stem Cell Cloning in Chronic Myeloid Leukemia

January 2, 2013

An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is…

Gene Therapy Finds New Life in an Old Home

November 10, 2022

An international symposium November 17-18, 2022 at UC San Diego will discuss current clinical trials using gene therapy, here and abroad.

Braking Mechanism Identified for Cell Growth Pathway Linked to Several Cancers

June 26, 2015

Researchers at University of California, San Diego School of Medicine have discovered a self-regulating loop in the Hippo pathway, a signaling channel garnering increased attention from cancer researchers due to its role in controlling organ size, cell proliferation and cell death.

Underlying Molecular Networks Suggest New Targets to Combat Brain Cancer

July 25, 2016

…with a survival rate generally less than 16 months. With no effective treatments available, a team including researchers from the San Diego Supercomputer Center (SDSC) at UC San Diego and John Wayne Cancer Institute at Providence Saint John’s Health Center sought to uncover several underlying molecular networks that may yield…

Gene Therapy Approach Shows Promise in Treating ALS

August 2, 2022

Researchers report that a gene therapy approach, developed at UC San Diego measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.

Women’s Wellness Day, Free to the Public on Saturday, April 13

March 28, 2013

…will host insightful talks on subjects, including stress reduction, gene therapy for heart repair, cancer prevention, successfully reducing menopause symptoms, and achieving longevity through diet and fitness.

Novel Study Identifies Key Molecular Players in Rheumatoid Arthritis

October 24, 2022

Using a novel systems biology approach, scientists at UC San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis, a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

In Multiple Myeloma, High Levels of Enzyme ADAR1 are Associated with Reduced Survival

December 5, 2017

Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

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