November 27, 2012
In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications – schizophrenia and bipolar disorder. In a new study, four of the antipsychotics most commonly prescribed off label for use in patients over 40 were found to…
February 8, 2016
…function. The new model could be used for patient-specific drug screening and disease modeling. Researchers said the advance could help pharmaceutical companies save time and money when developing new drugs.
September 16, 2013
Biologists at the University of California, San Diego have developed a revolutionary new method for identifying and characterizing antibiotics, an advance that could lead to the discovery of new antibiotics to treat antibiotic resistant bacteria.
June 19, 2012
Strains of bacteria able to resist multiple antibiotics pose a growing threat to public health, yet the means by which resistance quickly emerges aren’t well understood.
May 14, 2020
Using supercomputers, scientists have developed for the first time a way to screen drugs through their chemical structures for induced arrhythmias.
October 12, 2015
…why anemia is a common side effect of anti-cancer drugs that target enzymes involved in tumor growth.
July 21, 2016
…Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells. The study, published July 21 in Molecular Cell, uncovered 172 new combinations that could form the basis for future cancer therapies.
November 16, 2015
Peptides promise to be useful drugs, but they’re too easily digested and can’t get into cells without help. Chemists at UC San Diego now show that peptides can be protected from digestion and delivered into cells without changing their biological function by rearranging them into dense brushes.
September 16, 2015
…the healing power of drug treatments for cardiovascular disease and systemic bacterial infections. These nanoparticles are capable of delivering drugs to targeted sites in the body — particularly injured blood vessels and organs infected by harmful bacteria. This targeted drug delivery greatly increased the therapeutic effects of drugs administered to…
January 4, 2016
A team of researchers, with the aid of the Gordon supercomputer at the San Diego Supercomputer Center based at UC San Diego, has identified a class of possible antibiotics with the potential to disable previously drug-resistant bacteria.
