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Your search for “drug development” returned 1008 results

Older Adults with Functional Impairments Linked to Prescription Drug Use/Misuse

May 20, 2021

Researchers at University of California San Diego School of Medicine found that functional impairments among adults aged 50 and older are associated with a higher risk of medical cannabis use; and prescription opioid and tranquilizer/sedative use and misuse.

Nanospheres Safely Deliver High Chemotherapy Doses in Response to Tumor Secretions

July 14, 2015

Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize. That is, they have engineered a drug delivery system so that the very enzymes that make cancers dangerous could instead guide their destruction.

Roche Funds Drug Discovery Projects at UC San Diego

January 9, 2012

The new UC San Diego-Roche Extending Innovation Network (EIN) program has been launched with selection of its first three research projects at the University of California, San Diego School of Medicine.

Novel Anti-Malarial Drug Target Identified

July 19, 2012

…Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.

Popular Pharmaceutical Target in Cells May Prove Even More Useful

October 26, 2022

Researchers at UC San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs. The discovery opens the possibility of new therapies, including for multiple forms of cancer.

UC San Diego Health Researchers Join Pancreatic Cancer “Dream Team”

November 9, 2015

In an effort to advance research on one of the deadliest forms of cancer, University of California, San Diego School of Medicine researchers Andrew Lowy, MD, and Tannishtha Reya, PhD, have been recruited for their expertise in preclinical modeling, clinical trials and stem cell biology to join a “dream team”…

RNA-Based Drugs Give More Control Over Gene Editing

November 16, 2015

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University…

Phase III Clinical Trial to Evaluate Calcium Channel Blocker for Parkinson’s

September 30, 2014

…trial to evaluate the drug isradipine, a calcium channel blocker often used to treat high blood pressure, as a potential new treatment for Parkinson disease. The goal of the study is to determine whether the drug can slow the progression of the disease by keeping the brain’s dopamine-producing cells healthier…

Rapid Testing for TB Aims to Reduce Drug Resistance, Lower Mortality Rate

September 3, 2015

Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to global public health.

Cellular Atlas of Amygdala Reveals New Treatment Target for Cocaine Addiction

October 5, 2023

Researchers at University of California San Diego School of Medicine have used single-cell sequencing to identify a potential new treatment for cocaine addiction and shed new light on the molecular underpinnings of addiction.

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