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Your search for “neurodegenerative disease” returned 153 results

Degenerating Neurons Respond to Gene Therapy Treatment for Alzheimer’s Disease

August 27, 2015

Degenerating neurons in patients with Alzheimer’s disease (AD) measurably responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.

Historical Disease Meets Modern Biology in New Faculty Member Cressida Madigan’s Lab

July 2, 2020

Historical Disease Meets Modern Biology in New Faculty Member Cressida Madigan’s Lab New Biological Sciences faculty member Cressida Madigan doesn’t mind if an ancient disease such as leprosy is not something we think about every day. Influenced by her art historian parents and diseases that changed the course of world…

Neurological Disorder Impacts Brain Cells Differently

November 9, 2011

In a paper published in the November 9 issue of The Journal of Neuroscience, researchers at the University of California, San Diego School of Medicine and University of Washington describe in deeper detail the pathology of a devastating neurological disorder, but also reveal new cellular targets for possibly slowing its…

Scientists Discover New Genetic Forms of Neurodegeneration

January 30, 2014

In a study published in the January 31, 2014 issue of Science, an international team led by scientists at the University of California, San Diego School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia.

UC San Diego Receives Michael J. Fox Foundation Grant to Identify Parkinson’s Biomarkers

December 8, 2015

Parkinson’s disease is difficult to diagnose, particularly in its early stages. Now, researchers at University of California, San Diego School of Medicine – aided by a $375,000 grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) – hope to improve the prospects of early diagnosis by identifying a…

Single Gene Mutation Linked to Diverse Neurological Disorders

October 9, 2013

…other, diverse neurological disorders like Alzheimer’s, Parkinson’s and Huntington’s diseases.

A New View for Protein Turnover in the Brain

August 7, 2017

Scientists at UC San Diego have provided the first evidence that lysosomes, specialized structures found in nearly every cell in your body, can travel to distant parts of neurons to branch-like areas known as dendrites. Lysosomes help keep balance in the brain by removing material that is no longer needed,…

Model Maps Out Molecular Roots of Learning and Memory Formation

September 6, 2016

A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain. The research paves the way for understanding cognitive function and neurodegenerative diseases—at the molecular and cellular levels.

Poseidon Innovation Announces Funding for Three UC San Diego Researchers

June 26, 2020

UC San Diego and Deerfield Management created Poseidon Innovation to support researchers working to advance disease-curing therapeutics by funding early stage projects and expediting the drug-development cycle. Poseidon announces it is funding three researchers.

Multiple Pathways Progressing to Alzheimer’s Disease

June 25, 2015

UC San Diego School of Medicine researchers report that the amyloid cascade hypothesis, long believed to describe the pathology of Alzheimer’s disease, is not a fixed and invariable sequence of events. Rather, early indicators or biomarkers of the neurodegenerative condition vary by individual, making preclinical diagnoses more challenging.

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