September 27, 2016
The Howard Hughes Medical Institute (HHMI), the Simons Foundation and the Bill & Melinda Gates Foundation has named Samara Reck-Peterson, PhD, an HHMI-Simons Faculty Scholar. Reck-Peterson, a professor in the Department of Cellular and Molecular Medicine and Division of Biological Sciences at University of California San Diego, will receive a…
February 17, 2015
…(MAPT) gene as increasing the risk for developing Alzheimer’s disease (AD). The MAPT gene encodes the tau protein, which is involved with a number of neurodegenerative disorders, including Parkinson’s disease (PD) and AD. These findings provide novel insight into Alzheimer’s neurodegeneration, possibly opening the door for improved clinical diagnosis and…
May 4, 2021
Researchers at UC San Diego have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease, a key step toward eventually testing the approach in humans with the neurodegenerative disease.
July 11, 2018
Alzheimer’s disease is a progressive, neurodegenerative condition that often begins with mild cognitive impairment (MCI), making early and repeated assessments of cognitive change crucial to diagnosis and treatment. In a paper in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, researchers led by scientists at the University of California San…
December 15, 2022
Researchers at UC San Diego provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer’s, making it very difficult to identify in living patients.
June 22, 2014
Researchers at the University of California, San Diego School of Medicine have discovered a fundamental mechanism by which the brain maintains its internal balance. The mechanism, described in the June 22 advanced online publication of the journal Nature, involves the brain’s most basic inner wiring and the processes that control…
December 21, 2011
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder.
July 18, 2012
Using a two-photon microscope capable of peering deep within living tissue, researchers at the University of California, San Diego School of Medicine have found new evidence that alpha-synuclein protein build-up inside neurons causes them to not only become “leaky,” but also to misfire due to calcium fluxes.
October 14, 2013
Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called “master regulators” read the genome, and consequently turn genes on and off.
January 29, 2020
Researchers at UC San Diego School of Medicine, with colleagues, describe a new method for delivering neural precursor cells to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.
