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Your search for “Transplantation” returned 225 results

Antibody Breaks Leukemia’s Hold, Providing New Therapeutic Approach

October 27, 2016

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML. The study also…

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

August 28, 2017

More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year…

Beneficial Skin Bacteria Protect Against Skin Cancer

February 28, 2018

Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.

New Cancer Immunotherapy Approach Turns Immune Cells into Tiny Anti-Tumor Drug Factories

December 4, 2018

In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs.

Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer Cells

January 16, 2020

Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink…

Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins

July 2, 2021

UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.

Appendiceal Cancer Gets Its Own Preclinical Model

November 1, 2022

Researchers at UC San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe the first preclinical model of appendiceal cancer that contains all elements of the tumor, allowing previously stymied investigations to proceed.

Human Brain Organoids Implanted into Mouse Cortex Respond to Visual Stimuli for First Time

December 28, 2022

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli.

Enhancing the Experience of Diverse Asian American and Pacific Islander Students

February 21, 2023

To continue strengthening the student experience for Asian American and Pacific Islander students, UC San Diego has become designated as an Asian American and Native American Pacific Islander Serving-Institution (AANAPISI). This means that UC San Diego is now eligible to apply for federal grants.

Digitized Number 2: Stool Samples Reveal Microbial Enzyme Driving Bowel Disease

January 27, 2022

Researchers at UC San Diego used a multi-omics approach to investigate stool samples from patients with ulcerative colitis, a chronic inflammatory bowel disease. The team has identified the family of microbiome-derived enzymes driving the disease, and demonstrated a potential therapeutic solution.

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