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Your search for “Therapy Target” returned 457 results

Cancer Drug Could Ease Cognitive Function for Some With Autism

July 25, 2024

An experimental cancer drug could ease cognition for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the Muotri Lab at the University of California San Diego — a discovery that could lead to therapies for patients with other neurologic conditions.

$2M Grant Drives Research on Novel Insulin in Type 1 Diabetes

August 23, 2023

With funding from The Leona M. and Harry B. Helmsley Charitable Trust, Jeremy Pettus, MD, an associate professor of medicine and board-certified endocrinologist who specializes in treating diabetes at UC San Diego Health, is leading a study on Liver Targeted Insulin (LTI) in Type 1 diabetes.

Giant Viruses Build a Cell Nucleus Surprisingly Like Our Own

August 3, 2022

Scientists are using new technologies to obtain unprecedented looks inside viruses and their unique abilities to infect and destroy bacteria. Using cryo-EM and other technologies, they found that jumbo phage cells feature a compartment that is surprisingly similar to the nucleus of human cells.

UC San Diego-Human Longevity Inc. Agreement Seeks to Accelerate Medical Science

March 4, 2014

…the human genome into novel and real treatments and therapies able to change and improve the human condition.

Researchers Identify Liver Cancer Progenitor Cells Before Tumors Become Visible

October 10, 2013

Researchers at the University of California, San Diego School of Medicine have isolated and characterized the progenitor cells that eventually give rise to malignant hepatocellular carcinoma tumors – the most common form of liver cancer. The researchers found ways to identify and isolate the HCC progenitor cells long before actual…

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

February 18, 2021

UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

Nanosponges Soak Up Toxins Released by Bacterial Infections and Venom

April 14, 2013

Engineers at the University of California, San Diego have invented a “nanosponge” capable of safely removing a broad class of dangerous toxins from the bloodstream – including toxins produced by MRSA, E. coli, poisonous snakes and bees.

In Multiple Myeloma, High Levels of Enzyme ADAR1 are Associated with Reduced Survival

December 5, 2017

Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

With Gene Therapy, Scientists Develop Opioid-Free Solution for Chronic Pain

March 10, 2021

A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. By temporarily repressing a gene involved in sensing pain, the treatment increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.

Researchers identify a new culprit behind fibrosis

October 15, 2015

…fibrosis and paves the way toward new and improved therapies for the disease.

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