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Your search for “STEM” returned 868 results

Personalized “Eye-in-a-Dish” Models Reveal Genetic Underpinnings of Macular Degeneration

May 9, 2019

Using stem cells derived from six people, UC San Diego School of Medicine researchers recapitulated retinal cells in the lab. This “eye-in-a-dish” model allowed them to identify genetic variants that cause age-related macular degeneration, a common cause of vision loss.

Understanding a Protein’s Role in Familial Alzheimer’s Disease

November 14, 2013

…Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer’s disease (AD), discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

August 25, 2021

Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.

UC San Diego Health Treats 1st Cancer Patient with Stem-Cell Derived Natural Killer Cells

April 1, 2019

Moores Cancer Center at UC San Diego Health treats the first patient treated for cancer with a human-induced pluripotent stem cell (iPSC)-derived cell therapy called FT500. Dan Kaufman collaborated with Fate Therapeutics to bring the iPSC-derived natural killer cell cancer immunotherapy to patients.

Neurons Stripped of Their Identity Are Hallmark of Alzheimer’s Disease, Study Finds

November 13, 2020

UC San Diego researchers have identified new mechanisms in neurons that cause Alzheimer’s disease. In particular, they discovered that structural changes in chromatin trigger neurons to lose their specialized function and revert to a precursor-like state.

UC San Diego Nets Another Top Global Ranking

March 19, 2015

…the regenerative power of stem cells into real-world therapies, U.S. businessman and philanthropist T. Denny Sanford committed $100 million to the creation of the Sanford Stem Cell Clinical Center, a UC San Diego-based effort that will speed discoveries of new drugs and treatments for patients. UC San Diego is home…

Celebrating 20 Years of Sally Ride Science

February 18, 2021

…major milestone of providing STEM inspiration for the next generation The 2019 Women in Leadership event brought together (from left) astrophysicist Jedidah Isler; journalist Lynn Sherr, who served as moderator; former first daughter Chelsea Clinton; and Girl Scouts CEO Sylvia Acevedo. Candace Norton/Photo. After America’s first woman in space retired…

Building a Better Brain-in-a-Dish, Faster and Cheaper

September 6, 2018

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

Zika Virus Targets and Kills Brain Cancer Stem Cells

September 5, 2017

…report the virus specifically targets and kills brain cancer stem cells.

Preuss Scholars Train with Soccer Legends

August 5, 2024

In another example of community partnerships creating once-in-a-lifetime opportunities for scholars, The Preuss School UC San Diego hosted a soccer camp with legends from Manchester United Football Club on July 30 in collaboration with Qualcomm Inc.

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