Researchers Investigate How Staphylococcus Aureus Resists Vaccines
December 16, 2024
George Liu and lab members Irshad Hajam and Chih-Ming Liu at UC San Diego School of Medicine are making inroads into how Staphylococcus aureus evades vaccines.
Your search for “Staphylococcus Aureus” returned 38 results
How to Spot Patients Most Likely to Die from Blood Infections
September 3, 2020
…risk of dying from Staphylococcus aureus bacteremia—a leap forward toward a predictive tool that would allow clinicians to more quickly determine which patients require a more complex treatment regimen. So Gonzalez thought: What if a proteomic “readout” from a person’s blood could help identify who needs the most help early…
Distinguishing Deadly Staph Bacteria from Harmless Strains
June 6, 2016
…understand the pathogenic bacteria Staphylococcus aureus and develop more effective treatments, University of California San Diego researchers examined the Staph “pan-genome” — the genomes of 64 different strains that differ in where they live, the types of hosts they infect and their antibiotic resistance profiles. This effort, published June 6…
Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response
December 16, 2024
After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model.
Compound Discovered at Sea Shows Potency against Anthrax
July 17, 2013
…treatments for anthrax and other ailments such as methicillin-resistant Staphylococcus aureus (MRSA).
Presence of Staph Bacteria in Skin Microbiome Promotes Netherton Syndrome Inflammation
March 3, 2020
Netherton syndrome is exacerbated by the presence of Staphylococcus aureus and Staphylococcus epidermidis living on human skin report University of California San Diego School of Medicine researchers.
Transplanting Good Bacteria to Kill Staph
February 22, 2017
University of California San Diego School of Medicine researchers screened 10,000 colonies of bacteria found on the epidermis to determine how many had antimicrobial properties and at what rate these are found on healthy and non-healthy skin. In a paper published in Science Translation Medicine, the team reports isolating and…
UC San Diego Researchers Identify How Skin Ages, Loses Fat and Immunity
December 26, 2018
Some dermal fibroblasts can convert into fat cells that reside under the dermis, giving skin a youthful look and producing peptides that fight infections. University of California San Diego School of Medicine researchers and colleagues show how this happens and what causes it to stop as people age.
Cigarette Smoke Makes Superbugs More Aggressive
April 2, 2015
Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. Researchers at the University of California, San Diego School of Medicine now report that cigarette smoke may make matters worse. The study, published March 30 by Infection and Immunity, shows that MRSA…
We Need a Staph Vaccine: Here’s Why We Don’t Have One
January 16, 2024
A vaccine for Staphylococcus aureus, one of the most common bacterial infections, would be a game changer for public health. No vaccine candidates have succeeded in clinical trials, but nobody knows why. Researchers at UC San Diego may have figured it out.
