New Mouse Model Points to Therapy for Liver Disease
August 18, 2014
…both the development of NASH and its progression to liver cancer.
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Causes of Liver Cancer are Changing Around the World: Some Up, Some Down
June 6, 2022
UC San Diego researchers report that the causes and death rates of liver cancer are changing around the world.
Novel Antisense Drug Shows Promise in Slowing Fatty Liver Disease
June 16, 2020
A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form.
UC San Diego Launches New Nonalcoholic Fatty Liver Disease Research Center
February 8, 2016
…– have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure. Combining a diverse array of basic science, biomarkers, imaging and clinical efforts, University of California, San Diego School of Medicine has launched a new NAFLD Research Center to better understand…
Movement Toward a Poop Test for Liver Cirrhosis
March 29, 2019
In a study of people with nonalcoholic fatty liver disease and their twins and other close relatives, UC San Diego researchers were able to diagnose liver cirrhosis simply by analyzing a person’s stool microbes.
UC San Diego Researchers Awarded $889,000 for Cystinosis Studies
August 27, 2013
Two researchers at the University of California, San Diego School of Medicine have been awarded grants totaling more than $889,000 from the Cystinosis Research Foundation (CRF) to investigate better treatments and a cure for cystinosis. A rare and deadly genetic disease, cystinosis affects about 500 children and young adults in…
How Gene Therapy May Hold Key to Treating Life-Threatening Cardiac Disease
March 18, 2020
New study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models.
Molecular Link between Obesity and Type 2 Diabetes Reveals Potential Therapy
February 23, 2015
Researchers at University of California, San Diego School of Medicine have discovered that the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. What’s more, the team found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves…
Stool Microbes Predict Advanced Liver Disease
May 2, 2017
Nonalcoholic fatty liver disease (NAFLD) — a condition that can lead to liver cirrhosis and cancer — isn’t typically detected until well advanced. Even then, diagnosis requires a biopsy. To more easily detect NAFLD, UC San Diego School of Medicine researchers and their collaborators report that the microbial makeup of…
Two Novel Biobanks Offer Investigatory Targets for Cocaine and Oxycodone Addiction
April 26, 2021
Researchers have created to novel biobanks of diverse tissues from animals to further explore the biological bases and consequences of addiction to cocaine and oxycodone.
