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Your search for “Inflammation” returned 379 results

Gastrointestinal Hormone Measurably Improved Symptoms of Non-Alcoholic Fatty Liver Disease

March 8, 2018

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and…

UC San Diego Joins National Trial to Test Drug for Treating MPOX

October 27, 2022

UC San Diego will be one of multiple sites assessing the safety and efficacy of tecovirimat as a potential treatment for human monkeypox. Marketed as TPOXX, tecovirimat is an antiviral currently approved for treatment of human smallpox in adults and children caused by the variola virus.

Illicit Fentanyl Use Linked to Increased Risk of Hepatitis C Among People Who Use Drugs

July 30, 2024

Researchers from University of California San Diego and el Colegio de la Frontera Norte in Mexico have revealed a link between illicit fentanyl use and the transmission of hepatitis C (HCV) among people who inject drugs in San Diego, California and Tijuana, Mexico.

COVID-19, MIS-C and Kawasaki Disease Share Same Immune Response

May 16, 2022

COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.

Chasing Down a Cellular ‘Short Circuit’

June 4, 2024

A group of researchers at University of California San Diego has identified the cause of a “short-circuit” in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development of a wide array of new drugs.

Scientists Discover a New Signaling Pathway and Design a Novel Drug for Liver Fibrosis

April 25, 2024

Scientists from the University of California San Diego discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis.

Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease

March 2, 2021

Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.

Cannabis Research Buds Out in New Directions, Arthritis to Insomnia

October 10, 2019

…reducing pain, anxiety and inflammation. CMCR scientists are currently preparing studies to investigate CBD as a possible treatment option for autism and essential tremor, a nervous system disorder. Other studies are looking at the use of cannabis to alleviate pain. The five new studies focus on CBD as possible remedy…

Algae Shown to Improve Gastrointestinal Health

January 27, 2020

UC San Diego scientists have completed the first study in humans demonstrating that a common algae improves gastrointestinal issues related to irritable bowel syndrome. The green, single-celled organism called Chlamydomonas reinhardtii was found to help with diarrhea, gas and bloating.

Digitized Number 2: Stool Samples Reveal Microbial Enzyme Driving Bowel Disease

January 27, 2022

Researchers at UC San Diego used a multi-omics approach to investigate stool samples from patients with ulcerative colitis, a chronic inflammatory bowel disease. The team has identified the family of microbiome-derived enzymes driving the disease, and demonstrated a potential therapeutic solution.

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