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Your search for “Drug discovery” returned 447 results

One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice

June 24, 2020

UC San Diego researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.

SPARK Gala Returns April 25 to Support Cancer Research and Care

April 22, 2015

San Diego community members, physicians and cancer survivors will come together Saturday, April 25 at the Grand Del Mar for SPARK Gala, an evening to “ignite the fight against cancer.”

Scientists Race to Outpace Lethal Bacterial Infections

May 30, 2018

…between new antibiotics and drug-resistant bacteria—and scientists are challenged to keep up. By 2050, according to a Wellcome Trust study, deaths from deadly infections will be more common than cancer deaths. Scientists report that currently antimicrobial resistance causes 23,000 deaths annually in the U.S.; 700,000 deaths worldwide. Better methods to…

N Equals One: New Podcast Features Hot Topics in Health Sciences

March 10, 2016

…of one project, one discovery or one scientist. The name N Equals One alludes to truly personalized medicine, in which the experimental sample size (n) includes just one person—you. “We wanted to create a communications platform where science enthusiasts can listen, learn—and hopefully be entertained — at times when they…

SDSC’s Triton Resource Helps “Track” How Kinesin Molecules Move

December 6, 2011

Researchers at UC San Diego’s Department of Chemistry and Biochemistry, in collaboration with several universities in the U.S., United Kingdom, and Poland, have developed a new picture of how kinesin molecules move along microtubules, or tiny biological train tracks – and how they sometimes come to a halt, causing diseases…

UC San Diego Chemists Use Light to Pinpoint Gene Expression

February 13, 2018

Armed with skill, special tools and light, University of California San Diego Associate Professor Neal Devaraj and a group of his chemistry graduate students activated cellular gene expression with unique precision. By modifying messenger RNA (mRNA)—a group of molecules that carries genetic information from DNA to ribosomes where specifications of…

Study: Breast Cancer Drug Shows Potential for Rare Appendix Cancer

October 16, 2024

UC San Diego School of Medicine researchers discover a groundbreaking oral breast cancer drug that is also effective in treating a rare form of appendix cancer.

Three UC San Diego Undergraduates Awarded National Competitive Scholarships

May 13, 2013

Kaylan Agnew, Neil Sapra and Chiara Ricci-Tam are the University of California, San Diego’s latest undergraduates to be recognized with national competitive scholarship awards.

MicroRNA Specifically Kills Cancer Cells with Common Mutation

October 2, 2016

Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy. Researchers at University of California San Diego School of Medicine and Moores Cancer Center used microRNAs to systematically inhibit thousands…

Artificial Intelligence Catalyzes Gene Activation Research and Uncovers Rare DNA Sequences

May 18, 2023

Biologists have used machine learning, a type of AI, to identify “synthetic extreme” DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and found synthetic DNA sequences with activities that could be useful in biotechnology and medicine.

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