November 14, 2011
…on Faculty Research: Stem Cell Shu Chien University Professor & Chair Dr. Chien and his colleagues have developed an array system 〈with thousands of combinations〉 that allows the rapid determination of the optimum physical and chemical conditions that direct the differentiation of stem cells into specific cell types. The ability…
April 14, 2022
…storage within the intact cells of fruit flies. The new optical imaging tool from the lab of bioengineering professor Lingyan Shi at the University of California San Diego is already being used to untangle often discussed, yet mysterious, links between diet and things like obesity, diabetes and aging. The work…
February 18, 2015
Nearly every cell in our bodies carries the same genetic code. Yet different types of cells read the same DNA in widely different ways, influenced by chemical chemical tags that modify the genetic material without changing the underlying DNA sequence. Scientists today announced significant progress in the unraveling of the…
November 9, 2023
A new mathematical model predicts that mammalian sperm cells have two distinct swimming modes. This prediction opens new questions about potential connections between sperm cells’ motor activity and their transitions to hyperactivation phases that may play an important role in fertilization.
August 1, 2013
…reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem Cell. Their approach has broad applicability for the successful production of iPSCs for use in human stem cell studies and eventual cell therapies.
May 1, 2015
…to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week’s issue of Proceedings of the National Academy of Sciences, makes it possible to reprogram large parts of a cell’s signaling network instead of targeting only…
March 28, 2024
UC San Diego biologists have uncovered a quality control timing mechanism tied to cell division. The “stopwatch” function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
August 31, 2016
…easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue—by feeding them adenosine, a naturally occurring molecule in the body. The stem-cell-derived bone tissue helped repair cranial bone defects in mice without developing tumors or causing infection.
December 10, 2020
Researchers recently created detailed simulations on the Comet system at the San Diego Supercomputer Center showing how these stiff red blood cells flow through blood vessels, deforming and colliding along the way.
April 11, 2013
…mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release insulin. The discovery suggests a new therapeutic target for treating dysfunctional beta cells and type 2 diabetes, a disease affecting more than 25 million Americans.
