August 11, 2014
Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries. This Phase I clinical trial is recruiting eight patients for the 5-year study.
October 30, 2014
…of Age of Stem Cell Therapy Photos by Erik Jepsen/UC San Diego Publications With first clinical trials, UC San Diego pushes stem cell therapies into a new era of real-world application In 2004, the therapeutic potential of stem cells persuaded more than 7 million Californians to approve Proposition 71, which…
September 9, 2021
UC San Diego School of Medicine researchers will receive $6.4 million in National Institutes of Health grant funding to study how external signals and genetic variations influence the behavior of one cell type in particular: insulin-producing beta cells in the pancreas.
July 19, 2023
What causes certain individuals who experience a sudden decline in kidney function to develop kidney disease while others recover? A new study co-led by UC San Diego bioengineers could provide insight—at the single-cell level—into the underlying factors contributing to these divergent outcomes.
December 16, 2016
…developing a unique and innovative technology to study how cells migrate in a 3D environment. The work has applications for the study of cancers, wound healing and regenerative medicine.
January 14, 2016
…and methods for the isolation and characterization of liver cells that will help drive new research on liver biology, drug safety and efficacy, and the treatment of liver diseases.
July 10, 2018
…PD-L1 to blind T cells from functioning. PD-L1 protects tumors through a “molecular brake” known as PD-1. Researchers have found that some tumor cells display not only their PD-L1 weapon, but also the PD-1 brake, essentially becoming a neutralizing function. The unexpected mechanism could help determine whether a cancer patient…
July 5, 2012
In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.
August 20, 2015
…Diego has discovered that an important class of stem cells known as human “induced pluripotent stem cells,” or iPSCs, which are derived from an individual’s own cells, can be differentiated into various types of functional cells with different fates of immune rejection.
July 18, 2016
Biochemists at the University of California San Diego have developed artificial cell membranes that grow and remodel themselves in a manner similar to that of living mammalian cells.
