November 2, 2015
Researchers at the University of California, San Diego have developed a model that could be used to predict a drug’s side effects on different patients. The proof of concept study is aimed at determining how different individuals will respond to a drug treatment and could help assess whether a drug…
July 3, 2012
…the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease. One such type of cancer is called pediatric T cell acute lymphoblastic leukemia, or…
May 22, 2023
The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.
November 30, 2021
UC San Diego nanoengineers developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus—a naturally efficient vehicle for delivering genetic material such as RNA inside cells.
February 22, 2018
…dagger, and stabbing neighboring cells.” Intrigued, Cooper acquired some “predator” bacteria and placed them next to “prey” E. coli cells. He gave the predators a red and the prey a green fluorescent protein so that he could tell them apart in live-action movies. The “predator” bacteria did kill the E.…
May 21, 2015
Using human embryonic stem cells, researchers at University of California, San Diego School of Medicine and Moores Cancer Center and Sanford-Burnham Medical Research Institute created a model that allows them to track cellular behavior during the earliest stages of human development in real-time. The model reveals, for the first time,…
January 6, 2014
…has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells. This work is published in the Proceedings of the National Academy of Sciences the week of Jan. 6, 2014.
November 4, 2020
Finding just the right model to study human development—from the early embryonic stage onward—has been a challenge for scientists over the last decade. Now, bioengineers at the University of California San Diego have homed in on an unusual candidate: teratomas.
July 6, 2015
Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes — chemical modifications cells use to control which genes are turned on or off.
February 8, 2018
…at the root of cell formation. They found that DNA executes an unexpected architectural role in shaping the cells of bacteria. Studying the bacterium Bacillus subtilis, the researchers used an array of experiments and technologies to reveal that DNA, beyond serving to encode genetic information, also “pumps up” bacterial cells.
