September 15, 2014
During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. Researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging…
March 2, 2021
Tissues which consist largely of collagen were the focus of a recent collaborative study by a team from Stanford University and Purdue University. To accomplish their work, they used the Comet supercomputer at the San Diego Supercomputer Center at UC San Diego.
June 22, 2014
Biologists at UC San Diego have found the “missing link” in the chemical system that enables animal cells to produce ribosomes—the thousands of protein “factories” contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.
February 3, 2014
Researchers at the University of California, San Diego School of Medicine have identified a protein critical to hematopoietic stem cell function and blood formation. The finding has potential as a new target for treating leukemia because cancer stem cells rely upon the same protein to regulate and sustain their growth.
April 22, 2024
New research by scientists at University of California San Diego has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
January 13, 2014
In a paper published in this week’s Online Early Edition of PNAS, researchers from the University of California, San Diego School of Medicine identify a key gene receptor and signaling pathway essential to maintaining hESCs in an undifferentiated state.
May 5, 2015
Human pluripotent stem cells possess the ability to grow into almost any kind of cell, which has made them dynamic tools for studying early human development and disease, but much depends upon what they grow up in. Writing in the May 4 online issue of the journal Scientific Reports, researchers…
January 3, 2019
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.
April 13, 2017
Chinese hamster ovary (CHO) cells are the workhorses behind more than half of the top-selling biologics on the market today. Humira, Avastin and Rituxan are a few. Researchers at the UC San Diego CHO Systems Biology Center are developing new tools, such as genome-scale metabolic models, to optimize CHO cell…
June 4, 2024
Breakthrough one-time cancer treatment option for select patients with metastatic melanoma and solid tumors now offered at UC San Diego Health.
