April 15, 2014
April 15, 2014 —
Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long.
January 2, 2014
January 2, 2014 —
…from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies. Their discovery may also provide scientists with a better understanding of how tumors evade the human immune system when they spread throughout the body.
November 13, 2024
November 13, 2024 —
…of life on Earth. How did the first living cells come to exist? How did these early protocells develop the structural membranes necessary for cells to thrive and assemble into complex organisms? New research from UC San Diego has uncovered a plausible explanation involving the reaction between two simple molecules.
October 1, 2014
October 1, 2014 —
…advance treatments for type 1 diabetes. Using human stem cells, the team plans to culture bits of human pancreas in a dish and, using microfluidics, mimic blood flow through the islet.
January 30, 2014
January 30, 2014 —
In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by DNA damage, with important consequences for the body’s cellular response to chemotherapy.
June 18, 2015
June 18, 2015 —
Researchers at University of California, San Diego School of Medicine have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C. The finding is published June 18 by Cell.
December 11, 2017
December 11, 2017 —
Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer’s, Parkinson’s, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers have identified 35 different subtypes of neurons and glial cells and discovered…
August 13, 2014
August 13, 2014 —
…similar to advances with other kinds of tissue stem cells.
August 22, 2016
August 22, 2016 —
…widespread medical problems, scientists were uncertain about how these single-celled fungi reproduced in human or animal cells. But in a study that employed transparent roundworms, biologists at the University of California San Diego succeeded in directly observing how these microorganisms replicate and spread. And what they saw surprised them.
March 21, 2023
March 21, 2023 —
UC San Diego researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.