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Your search for “Monoclonal Antibodies” returned 56 results

Developmental Protein Plays Role in Spread of Cancer

June 14, 2013

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center…

Novel Approaches to Treating Alzheimer’s Disease Include Early Intervention

May 15, 2012

Researchers at the Comprehensive Alzheimer’s Program at the University of California, San Diego School of Medicine have announced two new clinical trials for patients with either mild to moderate Alzheimer’s disease (AD) and one trial for Mild Cognitive Impairment.

UC San Diego Researchers Launch Combination Drug Trial to Eradicate B-Cell Malignancies

March 9, 2018

…of a standard of care drug with a novel monoclonal antibody that target B-cell malignancies, which include leukemias and lymphomas.

Phase I Trial Finds Experimental Drug Safe in Treating Chronic Lymphocytic Leukemia

June 1, 2018

…Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.

UC San Diego Cancer Researchers Receive $4 Million CIRM Disease-Team Grant

December 13, 2013

Researcher Thomas J. Kipps, MD, PhD, professor of medicine and deputy director of research operations at UC San Diego Moores Cancer Center, is principal investigator for one of six “Disease Team” awards approved December 12 by the governing board of the California Institute for Regenerative Medicine (CIRM).

UC San Diego Biologists Produce Potential Malarial Vaccine from Algae

May 16, 2012

UC San Diego biologists have produced a potential malarial vaccine from algae, an achievement that could pave the way for the development of an inexpensive way to protect billions of people from the disease.

Quest for Edible Malarial Vaccine Leads to Other Potential Medical Uses for Algae

April 19, 2013

Can scientists rid malaria from the Third World by simply feeding algae genetically engineered with a vaccine? That’s the question biologists at UC San Diego sought to answer after they demonstrated last May that algae can be engineered to produce a vaccine that blocks malaria transmission. In a follow up…

The Mouse That ROR’ed

January 2, 2014

Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.

State’s Stem Cell Agency Awards $18.2 Million Grant for B Cell Cancer Clinical Trial

August 24, 2017

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

Embryonic Development Protein Active in Cancer Growth

March 5, 2012

A team of scientists at the University of California, San Diego Moores Cancer Center has identified a novel protein expressed by breast cancer cells – but not normal adult tissues – that could provide a new target for future anti-cancer drugs and treatments.

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