To better understand PLA2 enzymes and help drive therapeutic drug development, researchers at University of California, San Diego School of Medicine developed 3D computer models that show exactly how two PLA2 enzymes extract their substrates from cellular membranes. The new tool is described in a paper published online the week of Jan. 26 by the Proceedings of the National Academy of Sciences.
The San Diego Supercomputer Center (SDSC) at the University of California, San Diego is a partner in a new international collaboration to develop computational models and software for simulations of bifunctional catalysis, which is of high relevance for biomass conversion to liquid fuels and raw materials used in the chemical industry.
For the second time in five years, CSE Prof. Victor Vianu is the recipient of the ACM PODS Alberto O. Mendelzon Test-of-Time Award. The annual award goes to the author or co-authors of a paper published in the proceedings of the Principles of Database Systems (PODS) ten years earlier. The award goes to the paper that had "the most impact in terms of research, methodology, or transfer to practice over the intervening decade." After winning the Test-of-Time Award in 2010, Vianu will be honored at the 2015 SIGMOD PODS conference in Australia, when he accepts another Test-of-Time Award.
Andrew Alm Benson, a distinguished emeritus professor of biology at Scripps Institution of Oceanography, UC San Diego, and renowned as one of the world’s leading plant scientists of the twentieth century, died peacefully from natural causes on Jan. 16, 2015, at UC San Diego’s Thornton Hospital. He was 97.
On Jan. 23-25, more than 15 stroke survivors and their caregivers will go on a mini-vacation in La Jolla, CA, as part of a therapeutic retreat for those whose lives have been affected – sometimes turned upside down – by stroke. The 50s-themed stroke camp is being co-hosted by UC San Diego Health System, which has one of the nation’s first certified Comprehensive Stroke Centers.
Researchers at University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences and the Bridge Institute at the University of Southern California report the first crystal structure of the cellular receptor CXCR4 bound to an immune signaling protein called a chemokine. The structure answers longstanding questions about a molecular interaction that plays an important role in human development, immune responses, cancer metastasis and HIV infections.
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