UC San Diego Chemists Use Light to Pinpoint Gene Expression
Armed with skill, special tools and light, University of California San Diego Associate Professor Neal Devaraj and a group of his chemistry graduate students activated cellular gene expression with unique precision. By modifying messenger RNA (mRNA)—a group of molecules that carries genetic information from DNA to ribosomes where specifications of gene expression occur—the chemists were able to precisely trigger gene expressions at a specific time and place using laser light. This novel technique will ease future studies of individual protein functions in cells or tissues at different stages of biological development.