Single Injection Alleviates Chemotherapy Pain for Months in Mice
UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.