UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” found that the human protein also plays a role in promoting tumors, in addition to suppressing them.
Santa Ana winds, seasonal gusts of dry desert air that can bring havoc to Southern California, might become less common, especially in fall and spring, as the conditions that drive them change, according to a pair of researchers at Scripps Institution of Oceanography at UC San Diego.
Organic compounds from perfume, food, fabrics and soaps coat indoor surfaces. The film commonly found in our homes can impact the air we breathe and our health. Yet the details of how these compounds interact microscopically with indoor surfaces are not fully known. Researchers are learning more.
In a study published January 17, 2019 in Translational Psychiatry, researchers at University of California San Diego School of Medicine describe how, in a novel mouse model, epigenetic regulation negatively impacts a downstream gene specifically involved in neurodevelopment and associated behaviors.
A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.
Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.
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