Health & Behavior

Research

The Latest

Enhancer RNAs Alter Gene Expression

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules. The work, published online this week in the journal Nature, suggests modulation of “enhancer-directed RNAs” or “eRNAs” could provide a new way to alter gene expression in living cells, perhaps affecting the development or pathology of many diseases.

Potential New Way to Suppress Tumor Growth Discovered

Researchers at the University of California, San Diego School of Medicine, with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growth, opening the possibility of developing a new class of anti-cancer drugs.

Oncogene Mutation Hijacks Splicing Process to Promote Growth and Survival

An international team of researchers – led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine – has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

UC San Diego to Confer 8,085 Diplomas at 2013 Commencement Ceremonies

Celebrated speakers of the University of California, San Diego’s commencement series, including comedian Lewis Black, San Diego City Council member Sherri Lightner, former White House doctor Connie Mariano and former president of the 10 campus University of California system Richard Atkinson, will give the keynote address to 7,860 graduating students this June.

Cholesterol Sets Off Chaotic Blood Vessel Growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated development of blood vessels can feed the growth of tumors.

Stem Cell Injections Improve Spinal Injuries in Rats

An international team led by researchers at the University of California, San Diego School of Medicine reports that a single injection of human neural stem cells produced neuronal regeneration and improvement of function and mobility in rats impaired by an acute spinal cord injury (SCI).