Therapies that specifically target mutations in a person’s cancer have been much-heralded in recent years, yet cancer cells often find a way around them. To address this, researchers at University of California, San Diego School of Medicine and Moores Cancer Center identified a promising combinatorial approach to treating glioblastomas, the most common form of primary brain cancer. The study published May 5 by Oncotarget.
Writing in the May 7 online issue of American Journal of Geriatric Psychiatry, researchers at University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System suggest that people with PTSD may also be at risk for accelerated aging or premature senescence.
Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute have identified the molecular “glue” that builds the brain connections that keep visual images clear and still, even as objects or your eyes move. Using mouse models, the researchers demonstrate that image stabilization depends upon two proteins, Contactin-4 and amyloid precursor protein, binding during embryonic development.
Each year, more than 10 million Americans seek medical attention, often in emergency situations, for symptoms of intestinal blockages. Researchers at the University California, San Diego School of Medicine have identified an abnormal form of small bowel twisting (or volvulus) that may cause these painful obstructions. In contrast to other causes of bowel obstruction that are treated with bowel rest, these require immediate surgical care.
With the threat of multidrug-resistant bacterial pathogens growing, new ideas to treat infections are sorely needed. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report preliminary success testing an entirely novel approach — tagging bacteria with a molecular “homing beacon” that attracts pre-existing antibodies to attack the pathogens.
UC San Diego Health System and the City of El Centro have entered into a long-term management services agreement on behalf of El Centro Regional Medical Center (ECRMC), the city-owned hospital, with the goal of enhancing the delivery of high-quality health care to patients in the Imperial Valley.
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