Why the Flu Vaccine Is Less Effective in the Elderly
Around this time every year, the flu virus infects up to one-fifth of the U.S. population and kills thousands of people, many of them elderly. A study published by Cell Press on Dec. 15 in Immunity now explains why the flu vaccine is less effective at protecting older individuals. More broadly, the findings reveal novel molecular signatures that could be used to predict which individuals are most likely to respond positively to vaccination.