An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer’s disease (AD), based upon genetic information.
Graduate students at the University of California San Diego will stage an original work and performance on Thursday, March 23, in the Qualcomm Institute on the university campus. Their interdisciplinary work, “The Burden of Selfhood”, will explore the themes of feminism, identity and technology.
Standard antidepressant medications don’t work for everyone, and even when they do they are slow to kick in. In an effort to find better depression treatments, researchers at University of California San Diego School of Medicine discovered that inhibiting an enzyme called Glyoxalase 1 (GLO1) relieves signs of depression in mice. Moreover, inhibiting GLO1 worked much faster than the conventional antidepressant Prozac.
Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published March 20 in Nature Methods, uncovered 120 new opportunities for cancer drug development.
Kyoto University of Japan, one of the University of California San Diego’s international partners, will open an office in San Diego in early April, both campuses have announced.
UC San Diego graduate programs in engineering, medicine and social sciences are ranked in nation’s top 20 by U.S. News & World Report.
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