Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer’s disease (AD) and Down syndrome (DS).
The University of California, San Diego has received an Andrew W. Mellon Foundation New Directions Fellowship grant—an award intended to assist humanities scholars in acquiring systematic training outside their areas of special interest—for the first time. The $209,000 grant will support Department of History Professor Mark Hendrickson’s efforts to explore how the work of American mining engineers and geologists working abroad between 1880 and 1930 helped shape the development of 20th-century American capitalism, science and foreign policy.
Researchers at the University of California, San Diego School of Medicine have developed a novel method for assessing mortality risk in elderly patients with cancer who also suffer from other serious diseases or conditions. The prognostic model, they say, is more precise and provides a more useful tool for determining the best treatments when more than one disease is involved.
Chemists at the University of California San Diego have designed a set of molecules that promote microscopic, anatomical changes in neurons associated with the formation and retention of memories. These drug candidates also prevent deterioration of the same neuronal structures in the presence of amyloid-beta, a protein fragment that accumulates in the brains of people with Alzheimer's disease.
Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance the return of function.
Previous studies have shown that married patients with cancer fare better than unmarried cancer patients, surviving more often and longer. In a new study, published April 11 in the journal Cancer, researchers at University of California, San Diego School of Medicine report that the benefits of being married vary by race and ethnicity, with male non-Hispanic white bachelors experiencing the worst outcome.
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