What Makes Blood Vessels Leaky: New Insights for Sepsis Therapeutics
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
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Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing
UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.
Comet Supercomputer Used to Illustrate Methane Storage Applications
Methane storage applications are a key bridging technology to carbon-free chemical fuels. A first-year grad student at UCSD has worked with an international team on a study of zeolite-templated carbon as a gas-storage material. Comet allowed faster completion of their experiments.
Massive Study Links Nearly 600 Genomic Regions to Self-Regulating Behaviors
Researchers identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, such as addiction. With data from 1.5 million people of European descent, the effort is one of the largest genome-wide association studies to date.
Brain Organoids Mimic Head Size Changes Associated with Type of Autism
Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.
State Stem Cell Agency Funds Three New UC San Diego Projects
The California Institute for Regenerative Medicine has approved a trio of awards, totaling approximately $4 million, to UC San Diego School of Medicine researchers to advance studies of new stem cell-based treatments for multiple types of cancer and amyotrophic lateral sclerosis.
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